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僅供科研實驗：重組堿性成纖維細胞生長因子 rh bFGF
更新時間：2024-09-05   點擊次數：473次

僅供科研實驗：重組堿性成纖維細胞生長因子 rh bFGF

藥理研究表明，本藥對創(chuàng)傷修復過程的三個階段，即局部炎癥反應階段、細胞增殖分化及肉芽組織形成階段、組織重建階段均有不同程度的促進作用。在炎癥期，本藥對創(chuàng)傷細胞有明顯的趨向活性，刺激成纖維細胞，血管內皮細胞等向創(chuàng)傷部位移動。當細胞遷移至損傷部位時，開始進入增殖和修復期，其中最關鍵的步驟之一是肉芽組織的形成，肉芽組織的本質是大量的毛細血管和豐富的成纖維細胞，本藥正是成纖維細胞、血管內皮細胞及血管平滑肌細胞的高效促生長劑，能夠強烈促進新生毛細血管的形成，增加肉芽組織毛細血管數量和血液流量，改善創(chuàng)面微循環(huán)，為組織修復提供所必須的氧及豐富的營養(yǎng)物質；

 

 名稱：重組堿性成纖維細胞生長因子

英文名稱：Recombinant Human Fibroblast Growth Factor-basic(rh-bFGF)
來源：大腸桿菌
性狀：凍干粉
體系：凍干前為5 mM PB、pH7.4
分子量：17.2 kDa
純度：≥95%（SDS-PAGE檢測）
生物活性：EC50=0.25~1 ng/ml（1*106-4*106 U：小鼠BALB/c 3T3細胞的劑量依賴性增殖實驗）
內毒素：<1.0 EU/μg（kinetic LAL法檢測）
微生物：無菌（細胞培養(yǎng)級）規(guī)格：10ug、100ug、1mg
內毒素：<1.0EU/μg 蛋白
保存： -20℃
有效期：1年
使用方法：臨用前溶解，使用無菌去離子水溶解制成0.5 mg/ml濃度的儲備液備用

 

 

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