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人混合血清作用及相關產(chǎn)品
更新時間:2017-05-05   點擊次數(shù):1201次

人混合血清采用正常人血液為原料原料,經(jīng)無菌采集、分離、微孔過濾后而成。本產(chǎn)品無支原體、無病毒、無噬毒體、內(nèi)毒素含量低于1EU/ml,適用于細胞、組織器官培養(yǎng)、細胞株保藏、單抗研制,是醫(yī)院、科研院校、動物疫苗、生物制藥廠家重要培養(yǎng)基之一。

人混合血清的作用

一、提供基本營養(yǎng)物質(zhì):氨基酸、維生素、無機物、脂類物質(zhì)、核酸衍生物等,是細胞生長必須的物質(zhì)。

二、提供激素和各種生長因子:胰島素、腎上腺皮質(zhì)激素()、類固醇激素(雌二醇、睪酮、孕酮)等。生長因子如成纖維細胞生長因子、表皮生長因子、血小板生長因子等。

三、提供結(jié)合蛋白:結(jié)合蛋白作用是攜帶重要地低分子量物質(zhì),如白蛋白攜帶維生素、脂肪、以及激素等,轉(zhuǎn)鐵蛋白攜帶鐵。結(jié)合蛋白在細胞代謝過程中起重要作用。

四、提供促接觸和伸展因子使細胞貼壁免受機械損傷。

五、對培養(yǎng)中的細胞起到某些保護作用:有一些細胞,如內(nèi)皮細胞、骨髓樣細胞可以釋放蛋白酶,血清中含有抗蛋白酶成分,起到中和作用。這種作用是偶然發(fā)現(xiàn)的, 現(xiàn)在則有目的的使用血清來終止胰蛋白酶的消化作用。因為胰蛋白酶已經(jīng)被廣泛用于貼壁細胞的消化傳代。血清蛋白形成了血清的粘度,可以保護細胞免受機械損傷,特別是在懸浮培養(yǎng)攪拌時,粘度起到重要作用。血清還含有一些微量元素和離子,他們在代謝解毒中起重要作用,如SeO3,硒等。

人混合血清相關知識:

    血液凝固析出的淡黃色透明液體。如將血液自血管內(nèi)抽出,放入試管中,不加抗凝劑,則凝血反應被激活,血液迅速凝固,形成膠凍。其周圍所析出之淡黃色透明液體即為血清,也可于凝血后經(jīng)離心取得。在凝血過程中,纖維蛋白原轉(zhuǎn)變成纖維蛋白塊,所以血清中無纖維蛋白原,這一點是與血漿zui大的區(qū)別。而在凝血反應中,血小板釋放出許多物質(zhì),各凝血因子也都發(fā)生了變化。這些成分都留在血清中并繼續(xù)發(fā)生變化,如原變成,并隨血清存放時間逐漸減少以至消失。這些也都是與血漿區(qū)別之處。但大量未參加凝血反應的物質(zhì)則與血漿基本相同。為避免抗凝劑的干擾,血液中許多化學成分的分析,都以血清為樣品。 

人混合血清相關產(chǎn)品:

特級胎牛血清 100ml 用于嬌貴細胞培養(yǎng)、細胞株保存
 200ml  
 500ml  
特級新生牛血清 100ml  用于雜交瘤細胞、骨質(zhì)瘤細胞、原代、傳代細胞等細胞培養(yǎng)及疫苗、診斷試劑生物試劑等
 200ml  
 500ml  
馬血清 100ml  適用于科研、疫苗、診斷試劑生物試劑等
 200ml  
 500ml  
山羊血清 100ml  適用于科研、診斷試劑生物試劑等
 200ml  
 500ml  
驢血清 100ml  適用于科研、診斷試劑生物試劑等
 200ml  
 500ml  
豬血清 100ml  適用于科研、診斷試劑生物試劑等
 200ml  
 500ml  
無菌脫纖維綿羊血 100ml 適用于科研、診斷試劑生物試劑等
 200ml  
 500ml  
無菌脫纖維馬血 100ml  適用于科研、診斷試劑生物試劑等

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