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鼠抗人CD61單克隆抗體-2022產(chǎn)品更新
更新時間:2022-10-20   點擊次數(shù):719次

鼠抗人CD61單克隆抗體-2022產(chǎn)品更新


單克隆抗體是由單一B細胞克隆產(chǎn)生的高度均一、僅針對某一特定抗原表位的抗體。通常采用雜交瘤技術(shù)來制備,雜交瘤(hybridoma)抗體技術(shù)是在細胞融合技術(shù)的基礎(chǔ)上,將具有分泌特異性抗體能力的致敏B細胞和具有無限繁殖能力的骨髓瘤細胞融合為B細胞雜交瘤。


CD61是一種110 kDa膜糖蛋白,也稱為整合素β3鏈或GPIIIa。CD61可與整合素αV鏈(CD51)或整合素βIIb鏈(CD41,GPIIb)結(jié)合,形成細胞戰(zhàn)術(shù)素、纖維連接蛋白、纖維蛋白原、層粘連蛋白、基質(zhì)金屬蛋白酶-2、骨橋蛋白、骨調(diào)節(jié)蛋白、纖溶酶原、血小板反應(yīng)蛋白、玻璃體凝集素和血管性血友病因子的異二聚體受體,一些成纖維細胞、一些活化的白細胞和腫瘤細胞。GPllb llla(CD41-CD61)在血小板和巨核細胞潛能細胞中的分布受到限制,是血小板聚集所必需的。


鼠抗人CD61單克隆抗體.jpg



Catalog Number:  XF-22153A

Size: 100ug:  100ug 1mg/ml

Source:  Mouse
Purification method:  Purified by protein-A affinity chromatography

Isotype:  Mouse IgG1 kappa

Storage:  PBS with 0.1% sodium azide.Store at 2-8°C.

 

 

Immunogen:  N/A

Full name:  integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

Calculated molecular weight:  788 aa, 87 kDa

Uniprot:  P05106

Gene ID (NCBI):  3690

Gene symbol:  ITGB3

Synonyms:  CD61, GP3A, GPIIIa, Integrin beta 3, ITGB3

 

 

Species Specificity:  Human, Non-human primates;other species not tested

Positive FC detected in:  Human peripheral blood platelets

Recommended dilution:  This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

 


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