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重組抗胰蛋白酶(rh-AAT)價格

重組抗胰蛋白酶(rh-AAT)價格

產(chǎn)品時間:2024-07-31

簡要描述:

重組抗胰蛋白酶(rh-AAT)價格:重組抗胰蛋白酶(rh-AAT),也稱為重組人抗胰蛋白酶(Recombinant Human α-1 Antitrypsin, rh-AAT),是一種通過基因工程技術(shù)生產(chǎn)的絲氨酸蛋白酶抑制劑。

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重組抗胰蛋白酶(rh-AAT)價格


重組抗胰蛋白酶(rh-AAT),也稱為重組人抗胰蛋白酶(Recombinant Human α-1 Antitrypsin, rh-AAT),是一種通過基因工程技術(shù)生產(chǎn)的絲氨酸蛋白酶抑制劑。


功能與作用

抑制蛋白酶活性:rh-AAT主要抑制蛋白酶,尤其是嗜中性粒細胞彈性蛋白酶的活性。這種抑制作用對于保護組織器官不被蛋白酶過度水解至關(guān)重要。

防止組織損傷:在缺乏AAT的情況下,嗜中性粒細胞彈性蛋白酶會過度水解肺泡壁的彈性蛋白,導(dǎo)致肺氣腫、慢性阻塞性肺?。–OPD)等呼吸道并發(fā)癥。rh-AAT的補充能夠預(yù)防這些由蛋白酶過度活性引起的組織損傷。

保護肝臟:AAT的缺陷也可能導(dǎo)致肝細胞的損害,進而引發(fā)肝硬化。rh-AAT的應(yīng)用有助于保護肝臟免受此類損害。

應(yīng)用領(lǐng)域

科研實驗:rh-AAT廣泛用于細胞培養(yǎng)、試劑配制等科研生產(chǎn)、教學實驗中。它作為實驗工具,幫助研究人員深入了解蛋白酶抑制機制及其在疾病中的作用。

非臨床治療:盡管rh-AAT在科研領(lǐng)域具有廣泛應(yīng)用,但它并非用于臨床治療的藥物。其使用范圍嚴格限定在科研實驗內(nèi)。


名稱:重組抗胰蛋白酶

英文名稱:Recombinant Human α-1 Antitrypsin(rh-AAT)

性狀:凍干粉

分子量:43.2 kDa

純度:≥95%(SDS-PAGE檢測)

使用方法:無菌蒸餾水復(fù)溶(建議臨用復(fù)溶)

規(guī)格:500ug、1mg、10mg、100mg、1g

內(nèi)毒素:≤1EU/mg

保存: 凍干粉4-8℃

有效期:1年

用途:細胞培養(yǎng)、試劑配制等科研生產(chǎn)、教學實驗


注意事項:1. 科研實驗使用,非臨床治療使用。

2. 保存原則:復(fù)溶后的蛋白請酌情分裝后于-20℃保存,避免反復(fù)凍融

3. 避免使用強酸、強堿、強氧化劑、高濃度的有機溶劑等易引起蛋白質(zhì)變性的試劑。



重組抗胰蛋白酶(rh-AAT)價格

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