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重組人生長分化因子3（GDF3）

重組人生長分化因子3（GDF3）

產品時間：2024-08-21

簡要描述：

重組人生長分化因子3（GDF3）：重組人GDF3（重組人生長分化因子3）是由大腸桿菌原核表達系統(tǒng)制備的重組蛋白，是在符合GMP標準要求的潔凈間內由原核系統(tǒng)表達、經(jīng)分離純化和過濾除菌等步驟制成，分子量約為14.4 kDa。

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重組人生長分化因子3（GDF3）

重組人GDF3（重組人生長分化因子3）是由大腸桿菌原核表達系統(tǒng)制備的重組蛋白，是在符合GMP標準要求的潔凈間內由原核系統(tǒng)表達、經(jīng)分離純化和過濾除菌等步驟制成，分子量約為14.4 kDa。

 

表達宿主： E. coli

產品規(guī)格：10 μg、50 μg、250 μg、500 μg

保存緩沖液：50mM Tris.Cl, 1mM EDTA, pH8.5

 

保存條件

本產品經(jīng)無菌過濾后保存于-20℃冰箱，一般應避免反復凍融。建議將GDF3分裝成小份，每次使用一份。

 

質量檢測：

純度：經(jīng)SDS-PAGE電泳檢測純度>90%.

內毒素：小于1 EU/μg

穩(wěn)定性：樣品在-20℃保存12個月穩(wěn)定

 

生物學特性

功能：GDF-3在多種生物學過程中發(fā)揮重要作用，包括細胞生長、分化和組織修復等。它與其他TGF-β家族成員相似，具有促進細胞增殖和分化的能力。

表達部位：GDF-3在成年人的骨髓、脾臟、胸腺和脂肪組織中表達。

與疾病的關系：研究表明，GDF-3的表達在高脂喂養(yǎng)的野生型FABP4/aP2缺失小鼠中被上調，并與肥胖相關，但與2型糖尿病相關的高血糖/高胰島素血癥無關。



重組人生長分化因子3（GDF3）

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